The sex hormones include estrogen (which includes several types), progesterone, and testosterone. Certain types of estrogen are considered to be more beneficial than other types, and the healthy metabolism of estrogen is associated with fewer health risks. Estrogen is produced in both women and men, and inadequate estrogen metabolism is associated with hormonal imbalance in both sexes. I3C and DIM can improve estrogen metabolism. I3C is known to improve the ratio of estrogen types. 

About the Formula

• Calcium D-Glucarate glucaric acid is found in our bodies as well as in fruits and vegetables such as oranges, apples, brussel sprouts, broccoli, and cabbage. Calcium D-glucarate might lower estrogen levels, and this is thought to be helpful in supporting some people with hormone deficiencies.
• CurcuWINTM Turmeric Extract is derived from the spice turmeric. It scavenges free radicals and also may have an indirect antioxidant effect by stimulating the synthesis of glutathione. CurcuWINTM also has the reputation of being anti-inflammatory and protective of the digestive tract. Many in vitro studies show that curcumin may support immune function.
• Green tea (and its active polyphenolic component EGCG) is derived from the same plant as black and oolong teas: Camellia sinensis. Green tea, unlike black and oolong tea, is not fermented after being picked, therefore, the active components of the herb remain unchanged. Green tea is an antioxidant, stimulates detoxication, improves the lipid proles, and has immune-stimulating effects.
• Resveratrol is a polyphenolic compound most associated with grapes, red grape juice, and red wine. It is also said to improve cardiovascular health and improve blood ow to the brain.
• DIM is a plant-derived compound that enhances estrogen metabolism causing a beneficial shift in the balance of estrogen, testosterone, and progesterone in men and women. Hormone balance is necessary for prostate, ovarian, uterine, cervical, and breast health.
• Indole 3 carbinol (I3C) is a phytochemical found naturally in cruciferous vegetables like broccoli, cabbage, brussel sprouts, and kale. I3C is closely related to DIM, as I3C is transformed by the action of stomach acid into DIM. I3C and DIM increase the activity of certain liver enzymes which can help to eliminate toxins and carcinogens.
• i-SabiTM is a natural dietary ingredient made from the rhizomes of pure Wasabia japonica. i-SabiTM provides a full spectrum of ITCs that supports your immune system, detoxifies and maintains healthy liver function, and provides strong antioxidant activity for cellular health.
• Tocotrienols are members of the vitamin E family of nutrients. Tocotrienols possess antioxidant properties against lipid peroxidation. Therefore they are used in the prevention of atherosclerosis and maintaining a healthy cardiovascular system.
• Bioperine® (black pepper fruit extract) is thought to enhance the absorption of other nutrients, like curcumin, into the bloodstream. Some studies have shown that Bioperine can increase Curcumin absorption by over 30%